DSM265 NEW
| Price | $30 | $64 | $89 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-25 |
Product Details
| Product Name: DSM265 | CAS No.: 1282041-94-4 |
| Purity: 99.79% | Supply Ability: 10g |
| Release date: 2025/07/25 |
Product Introduction
Bioactivity
| Name | DSM265 |
| Description | DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infections. |
| In vivo | In NOD-scid IL-2Rγnull (NSG) mice (23-36 g), DSM265 (0.5 - 75 mg/kg; oral administration; twice daily; for 4 days) exhibited potent antimalarial activity[2]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : < 0.1 mg/mL (insoluble.) Ethanol : 5 mg/mL (12.04 mM), Sonication is recommended. DMSO : 30 mg/mL (72.23 mM), Sonication is recommended. |
| Keywords | PfDHODH | P. falciparum 3D7 parasites | P. falciparum | DSM-265 | DSM265 | DSM 265 | DHODH |
| Inhibitors Related | Kaempferol | Kojic acid | Rotenone | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Artemisinin | Benzyl benzoate | Isomalt | DL-Methionine |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Mitochondria-Targeted Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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