Dopamine D4 receptor antagonist-1 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Dopamine D4 receptor antagonist-1 | CAS No.: 444724-92-9 |
| Supply Ability: 10g | Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Dopamine D4 receptor antagonist-1 |
| Description | Dopamine D4 receptor antagonist-1 can be used in schizophrenia study. Dopamine D4 receptor antagonist-1 is a selective antagonist of Dopamine D4 receptor (DRD4). The Ki value of Dopamine D4 receptor antagonist-1 for Hd4.2 is 9.0 nM [1]. |
| In vivo | Dopamine D4 receptor antagonist-1, administered intraperitoneally at a dosage of 10 mg/kg in a single dose, exhibits an inhibitory effect on catecholaminergic systems, specifically leading to increased dopamine (DOPA) accumulation in the hippocampus, with no significant effect on the striatum [1]. This observation was made in male Long-Evans rats weighing 180-250 g, dopamine D4 receptor locus knockout mice (D4 KO), and wild-type rats (WT). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
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TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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