
DHODH-IN-15 NEW
Price | $117 | $268 | $395 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-04-30 |
Product Details
Product Name: DHODH-IN-15 | CAS No.: 1364791-88-7 |
Purity: 97.26% | Supply Ability: 10g |
Release date: 2025/04/30 |
Product Introduction
Bioactivity
Name | DHODH-IN-15 |
Description | DHODH-IN-15 is the hydroxyfuran analogue of A771726. DHODH-IN-15 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 11 μM for rat liver DHODH. DHODH-IN-15 can be used for rheumatoid arthritis. |
In vitro | DHODH-IN-15 is a hydroxyfuran analogue of A771726, in which the biphenyl skeleton does not carry any substituents. Turning to the derivative DHODH-IN-15, no major differences were observed between the poses obtained on 1UUO and 1D3G. In both cases, DHODH-IN-15 was found to bind in a BQN-like manner, ie, the deprotonated hydroxyfuran part faced Arg136, thus effectively mimicking the carboxyl groups of BQN and related compounds. On 1D3G and 1UUO, in any case, no interaction of Tyr356 with Leflunomide was found, but when 2BXV was used as a docking target, a large part of this posture was found[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 55 mg/mL (195.54 mM), Sonication is recommended. |
Keywords | Rat liver DHODH | DHODH-IN-15 | DHODHIN15 | DHODH IN 15 | DHODH |
Inhibitors Related | Disulfiram | Methotrexate | Rotenone | Mycophenolate Mofetil | Ribavirin | Mycophenolic acid | 4-Diethylaminobenzaldehyde | Benzyl alcohol | Isomalt | Isoniazid | D-Mannitol | Ivosidenib |
Related Compound Libraries | Bioactive Compound Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | Mitochondria-Targeted Compound Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$70.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-04-27 | |
$2140.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-04-27 | |
$/ |
VIP5Y
|
RongNa Biotechnology Co.,Ltd
|
2025-04-29 | |
$117.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-04-28 |
- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY