Desethyl chloroquine diphosphate NEW
| Price | $1139 | $1819 | $2728 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-16 |
Product Details
| Product Name: Desethyl chloroquine diphosphate | CAS No.: 247912-76-1 |
| Purity: 99.72% | Supply Ability: 10g |
| Release date: 2025/07/16 |
Product Introduction
Bioactivity
| Name | Desethyl chloroquine diphosphate |
| Description | Desethyl chloroquine diphosphate, the active metabolite of Desethylchloroquine, is a cross-placental and orally available inhibitor of toll-like receptors (TLRs) with antiplasmodial activity and inhibition of autophagy. |
| In vivo | In the study, amochloroquine was administered by intraperitoneal injection to wild-type mice and Huntington's chorea mice. Levels of amochloroquine and its metabolites were compared in blood, brain and muscle tissue using LC-MS/MS (liquid chromatography-mass spectrometry) techniques. Despite the low concentrations of amochloroquine (5-15 μM), amochloroquine was more stable in the brain than in blood and muscle from 4 to 24 hours after administration. At the same time, Desethyl chloroquine (the active metabolite of amochloroquine) concentrations in blood and muscle decreased after 24 hours, while concentrations in the brain were lower and increased slightly during this period. Desethyl chloroquine diphosphate is a salt form of Desethyl chloroquine. [2] |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 1 mg/mL (2.05 mM), Sonication is recommended. H2O : 10 mg/mL (20.5 mM), Sonication is recommended. |
| Keywords | Desethyl chloroquine |
| Inhibitors Related | Stavudine | Kojic acid | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Doxycycline | Taurine | Valproic Acid | Paeonol | Naringin | Salicylic acid | Gefitinib |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $/ |
VIP5Y
|
RongNa Biotechnology Co.,Ltd
|
2025-04-29 | |
| $99.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co Ltd
|
2024-11-26 | |
| $50.00/1kg |
VIP6Y
|
Hebei Yanxi Chemical Co., Ltd.
|
2023-10-09 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY