![Cucurbit[8]uril](/ProductImageEN1/2025-07/Large/17418338-65dc-483a-b6c4-9932182972ea.png)
![Cucurbit[8]uril](/ProductImageEN1/2025-07/Small/17418338-65dc-483a-b6c4-9932182972ea.png)
Cucurbit[8]uril NEW
| Price | $41 | $57 | $135 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-02 |
Product Details
| Product Name: Cucurbit[8]uril | CAS No.: 259886-51-6 |
| Purity: 98.74% | Supply Ability: 10g |
| Release date: 2025/07/02 |
Product Introduction
Bioactivity
| Name | Cucurbit[8]uril |
| Description | Cucurbit[8]uril is a highly effective and safe supramolecular compound that promotes protein heterodimerization. It selectively induces the heterodimerization of methylviologen and naphthalene functionalized proteins, demonstrating its specificity and versatility. Additionally, Cucurbit[8]uril shows exceptional oral activity and low toxicity, making it a promising candidate for various pharmaceutical and biotechnological applications. |
| In vitro | Cucurbit[8]uril (0~20 μM; 48 hours; CHO-K1 cells) marginally reduces cell viability to 86%[2]. It selectively induces heterodimerization of MV-eYFP with Np-eCFP and high energy transfer between the proteins, observed only with all three supramolecular components forming the ternary complex. Cucurbit[8]uril inhibits unspecific protein assembly induced by methylviologen and enables the formation of selective protein heterodimers with more hydrophobic proteins. It prevents MV-induced unspecific dimerization with hydrophobic protein surfaces[1]. |
| In vivo | Cucurbit[8]uril exhibits minimal toxicity when administered either intravenously or orally in mice, as demonstrated by in vivo studies[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : < 1 mg/mL |
| Keywords | supramolecular | potent | orally | naphthalene | methylviologen | low-toxicity | Inhibitor | inhibit | heterodimerization | Cucurbit[8]uril |
| Related Compound Libraries | Macrocyclic Compound Library | Bioactive Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1970.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-07-18 | |
| $2.00/100kg |
VIP1Y
|
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
|
2025-06-30 | |
| $5.00/10mg |
VIP3Y
|
Anko Intermational Trade Limited
|
2023-04-12 | |
| $1.10/1g |
VIP5Y
|
Dideu Industries Group Limited
|
2022-07-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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