
Cloperastine hydrochloride
Price | Get Latest Price | ||
Package | 1kg | 10kg | 50kg |
Min. Order: | 1kg |
Supply Ability: | 20 tons |
Update Time: | 2025-07-06 |
Product Details
Product Name: Cloperastine hydrochloride | CAS No.: 14984-68-0 |
EC-No.: 239-067-8 | Min. Order: 1kg |
Purity: 99.99% | Supply Ability: 20 tons |
Release date: 2025/07/06 |
Cloperastine inhibits the hERG K + currents in a concentrationdependent manner with an IC 50 value of 27 nM.Among the antitussive agents, Cloperastine, which possesses antitussive and antiedemic activity, also relaxes the bronchial musculature. Cloperastine is a drug with a central antitussive effect, and is also endowed with an antihistaminic and papaverine-like activity similar to codeine but without its narcotic effects.
Intheanesthetizedguineapigs,Cloperastineatatherapeuticdoseof1mg/kgprolongedtheQTintervalandmonophasicactionpotential(MAP)durationwithoutaffectingPRintervalorQRSwidth.CloperastinehydrochlorideshowsrelativelylowacutetoxicChemicalbookitywhenadministeredbytheintraperitonealrouteinratsandmice,andshowsminortoxicitybytheoralroutewhenadministeredasCloperastinefendizoate,theLD50inratsandmiceforthetwoadministrationroutesexceeds1000and2000mg/kg,respectively.
Brand: Soarwin
CAS No.:14984-68-0
EC Number:239-067-8
Molecular Formula: C20H25Cl2NO
Melting point:147.9°
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- Since: 2025-02-19
- Address: 10-11, Building 4, No. 18 Jinshan Road, Longxi Street, Yubei District, Chongqing, China
+86-15790943001
crystal@sorawin.cn