Clofibric acid NEW
| Price | $70 |
| Package | 5g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Clofibric acid | CAS No.: 882-09-7 |
| Purity: 99.68% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Clofibric acid |
| Description | Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE. |
| In vitro | Clofibric acid enhances the expression of carbonyl reductase in vivo, reduces PGE2 levels, and diminishes the quantity of vascular endothelial growth factor (VEGF) in OVCAR-3 tumors and DISS-origin ascites. In solid OVCAR-3 tumors, it decreases microvascular density and induces apoptosis. Compared to the control, a 9,000 ppm Clofibric acid diet significantly reduces the growth of OVCAR-3 tumor xenografts s.c. by 46% and notably prolongs the survival of mice with DISS-origin malignant ascites. |
| In vivo | Clofibric acid enhances the expression of the CYP4A6 gene in RK13 cells transfected with PPAR-Gamma. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 40 mg/mL (186.35 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : 45 mg/mL (209.64 mM), Sonication is recommended. |
| Keywords | PPAR | Peroxisome proliferator-activated receptors | Inhibitor | inhibit | DrugMetabolite | Drug Metabolite | Clofibric acid |
| Inhibitors Related | PHYTOL | Mycophenolate Mofetil | Clozapine N-Oxide | Daidzein | Fenofibrate | Isonicotinic acid | 5-Aminosalicylic Acid | Naringenin | Ampyrone | Fisetin | 2,3-Butanediol | Icariin |
| Related Compound Libraries | Pesticide Compound Library | Glycometabolism Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Approved Drug Library | Anti-Obesity Compound Library | Drug Repurposing Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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