cis-Epoxysuccinic acid NEW
| Price | $42 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-31 |
Product Details
| Product Name: cis-Epoxysuccinic acid | CAS No.: 16533-72-5 |
| Supply Ability: 10g | Release date: 2025/07/31 |
Product Introduction
Bioactivity
| Name | cis-Epoxysuccinic acid |
| Description | cis-Epoxysuccinic acid is a potential agonist of Succinate receptor 1 and inhibitor of Isocitrate lyase 1 for use in biochemical experiments. |
| In vitro | In vitro, cis-Epoxysuccinic acid acts as a potent agonist of the succinate receptor (SUCNR1), with enhanced efficacy across several assays (e.g., cAMP inhibition, calcium mobilization, TGF-α shedding, and β-arrestin-3 recruitment). Cis-Epoxysuccinic acid suppresses cAMP levels with an EC?? of 2.7?μM (pEC?? = 5.57), making Cis-Epoxysuccinic acid approximately 10–20 times more potent than succinic acid[1]. |
| In vivo | In vivo, cis-Epoxysuccinic acid significantly increases blood pressure in rats via SUCNR1 activation, demonstrating comparable potency to succinic acid[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 200 mg/mL (1514.35 mM), Sonication is recommended. |
| Keywords | PLX-7683 | PLX 7683. | cis-Epoxysuccinic acid |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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