Cefamandole Overview

Definition:
Cefamandole is a second-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.

Function:
Cefamandole is effective against a broad spectrum of both gram-positive and gram-negative bacteria. It has enhanced activity against certain pathogens compared to first-generation cephalosporins and is also more stable against beta-lactamase enzymes.

Applications:

· Respiratory infections: Used to treat pneumonia, bronchitis, and other lower respiratory tract infections.

· Urinary tract infections (UTIs): Effective for both complicated and uncomplicated UTIs.

· Skin and soft tissue infections: Treats infections such as cellulitis and abscesses.

· Intra-abdominal infections: Used for conditions like peritonitis.

· Sepsis and bloodstream infections: Effective in managing bacteremia caused by susceptible bacteria.