CDK4/6-IN-7 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: CDK4/6-IN-7 | CAS No.: 2649120-20-5 |
| Supply Ability: 10g | Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | CDK4/6-IN-7 |
| Description | CDK4/6-IN-7, a highly potent and selective orally active inhibitor of CDK4/6, demonstrates impressive inhibition activity with IC50 values of 1.58 nM and 4.09 nM respectively. This compound is particularly valuable for breast cancer research [1]. |
| In vitro | CDK4/6-IN-7 (compound 7c) impairs MCF-7 cell viability with an IC?? value of 0.92 μM after 48 hours of exposure to concentrations ranging from 0.1 to 656.1 μM, as observed in a cell proliferation assay [1]. |
| In vivo | CDK4/6-IN-7 (compound 7c), when administered orally at 50 mg/kg daily for seven days, significantly inhibits tumor growth with a 57.68% inhibition rate in MCF-7 tumor-bearing female nude mice (aged 5 weeks), demonstrating both efficacy and tolerability. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $115.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
| $329.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2025-04-27 | |
| $390.00/100g |
VIP2Y
|
R&D Scientific Inc.
|
2025-03-28 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY