Carbonic anhydrase inhibitor 12 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-02 |
Product Details
| Product Name: Carbonic anhydrase inhibitor 12 | CAS No.: 2883451-38-3 |
| Supply Ability: 10g | Release date: 2025/05/02 |
Product Introduction
Bioactivity
| Name | Carbonic anhydrase inhibitor 12 |
| Description | Carbonic Anhydrase Inhibitor 12 is a potent inhibitor of CA II, with additional inhibitory activity against CA I, exhibiting K_i values of 1.72 nM for CA II and 271 nM for CA I. Moreover, it demonstrates significant anticancer activity across various cancer cell lines [1]. |
| In vitro | Compound 14h, a carbonic anhydrase inhibitor 12 at a concentration of 10 μM for 48 hours (single dose), significantly affects the specificity and the inhibitory potency across various cancer cell lines [1]. At concentrations of 2.4 μM in MCF-7 and 2.5 μM in MDA-MB-231 for the same duration, the compound induces cell cycle arrest at the G2/M phase and increases both early and late apoptotic phases relative to control untreated cells [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | CarbonicAnhydrase | Carbonic Anhydrase |
| Inhibitors Related | Benzenesulfonamide | Urea | Cyclamic acid sodium | Ellagic acid | Hydrochlorothiazide | Orthanilamide | Zonisamide | Tioxolone | Histone acetyltransferase p300 Inhibitor 4c | EMAC10101d | pNNP | Levosimendan |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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