Product Details
Product Name:
Buloxibutid |
CAS No.:
477775-14-7 |
Purity:
98.58% |
Supply Ability:
10g |
Release date:
2025/05/16 |
Product Introduction
Bioactivity
Name | Buloxibutid |
Description | Buloxibutid (AT2 receptor agonist C21) is a novel and selective small molecule angiotensin II AT2 receptor agonist, exhibiting Ki values of 0.4 nM and 10 μM for AT2 and AT1 receptors, respectively. |
In vivo | Buloxibutid, with an oral bioavailability of 20-30% and a 4-hour half-life in rats, induces neurite cell outgrowth, stimulates p42/p44mapk, enhances in vivo duodenal alkaline secretion in Sprague-Dawley rats, and lowers mean arterial blood pressure in anesthetized, spontaneously hypertensive rats. [1] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 22.5 mg/mL (47.31 mM), Sonication is recommended.
|
Keywords | Buloxibutid | AT2 receptor | AT2 | AT1 |
Inhibitors Related | Olmesartan Medoxomil | Losartan potassium | Tranilast | Enalapril Maleate | Azilsartan Methyl Ester | Sacubitril/Valsartan | Azilsartan | Irbesartan | Losartan | Ramipril | Captopril | Valsartan Methyl Ester |
Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Endocrinology-Hormone Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$42.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-05-16 |