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Postion:Product Catalog >BPH-1358 free base
BPH-1358 free base
  • BPH-1358 free base

BPH-1358 free base NEW

Price $1520 $1980 $2500
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-19

Product Details

Product Name: BPH-1358 free base CAS No.: 801985-13-7
Supply Ability: 10g Release date: 2025/07/19

Product Introduction

Bioactivity

NameBPH-1358 free base
DescriptionBPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL).
In vitroBPH-1358 is the most potent inhibitor of both E. coli UPPS (EcUPPS) and S. aureus UPPS (SaUPPS) with an IC50 of 110 nM and EC50s of 300 nM and 290 nM, respectively, against E. coli and S. aureus [1].
In vivoIn an i.p. infection model with an MRSA strain, BPH-1358 is active against S. aureus (20/20 mice survived) [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
KeywordsNSC-50460 | NSC50460 | NSC 50460 | human bisphosphonate farnesyl diphosphate synthase | BPH-1358 free base | BPH1358 free base | BPH-1358 | BPH1358 | BPH 1358 free base | BPH 1358

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
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