
BMT-090605 NEW
Price | $2120 | $2780 | $3700 |
Package | 25mg | 50mg | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-18 |
Product Details
Product Name: BMT-090605 | CAS No.: 1551403-51-0 |
Supply Ability: 10g | Release date: 2025/07/18 |
Product Introduction
Bioactivity
Name | BMT-090605 |
Description | BMT-090605 is a potent, selective AAK1 inhibitor with an IC50 of 0.6 nM, and inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 45 and 60 nM, respectively[1]. BMT-090605 also exhibits antinociceptive activity. |
In vitro | BMT-090605 shows a cellular IC50 of 0.63 ±0.39 nM for AAK1[1]. |
In vivo | BMT-090605 (0.3-3 μg/rat; intrathecally at lumbar level L5/L6) causes antinociception by inhibiting AAK1 in the spinal cord[1]. Exposure measurements from this study indicated that brain and plasma levels of BMT-090605 were <4 nM, whereas measurable levels (90–317 nM) were observed in lumbar spinal cord[1]. The high dose of BMT-090605 (3 μg/rat) showed efficacy comparable to intrathecal clonidine (3 μg/rat). |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | BMT 090605 | BMT090605 | BMT-090605 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$3610.00/100mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-07-21 | |
$38.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$3.70/1kg |
VIP5Y
|
Hebei Chuanghai Biotechnology Co,.LTD
|
2024-08-09 | |
$2120.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-07-26 |
- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY