
BMS-191095 NEW
Price | $88 | $213 | $322 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-03 |
Product Details
Product Name: BMS-191095 | CAS No.: 166095-21-2 |
Purity: 100% | Supply Ability: 10g |
Release date: 2025/07/03 |
Product Introduction
Bioactivity
Name | BMS-191095 |
Description | BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator. |
In vitro | BMS-191095 elicits a dose-dependent vasodilation in endothelium-denuded cerebral arteries with 8.1 ± 2.3%, 31.6 ± 2.1%, and 39.5 ± 3.2% relaxation in response to 10, 50, and 100 μM, respectively. BMS-191095 induces mitochondrial-depolarization and vasodilation. |
In vivo | In normal rats, BMS-191095-induced vasodilation was mediated by mitochondrial depolarization and calcium sparks generation in VSM and was reduced by inhibition of BKCa channels. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 90 mg/mL (220.11 mM), Sonication is recommended. |
Keywords | PotassiumChannel | Potassium Channel | KcsA | Inhibitor | inhibit | BMS-191095 | BMS191095 | BMS 191095 |
Inhibitors Related | Minoxidil sulfate | Tannic acid | Hydrochlorothiazide | (±)-Naringenin | Tetraethylammonium bromide | Halothane | Butamben | Ursodeoxycholic acid | Cloperastine hydrochloride | Minoxidil | Nifedipine | Indapamide |
Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Neuroprotective Compound Library | NO PAINS Compound Library | Mitochondria-Targeted Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Potassium Channel Targeted Library | Ion Channel Targeted Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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