Betahistine dihydrochloride NEW
| Price | $29 |
| Package | 1mL |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-01 |
Product Details
| Product Name: Betahistine dihydrochloride | CAS No.: 5579-84-0 |
| Purity: 99.88% | Supply Ability: 10g |
| Release date: 2025/05/01 |
Product Introduction
Bioactivity
| Name | Betahistine dihydrochloride |
| Description | Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. |
| In vitro | In mice, Betahistine (ED50=2 mg/kg) elevates t-MeHA levels in a dose-dependent manner. In patients with Ménière's disease, Betahistine (16 mg, twice daily for 3 months) significantly alleviates vertigo. Additionally, Betahistine (50 mg/kg) induces an upregulation of histidine decarboxylase mRNA in the nodose ganglion of the cat brain. |
| In vivo | In CHO(H3R) cells treated with 3 μM of, Betahistine progressively increased cAMP formation, peaking at 10 nM. Furthermore, in CHO(H3R) cells, Betahistine progressively reduced A23187-induced [3H]arachidonic acid release (EC50=0.1 nM), with the greatest effect observed at 30 nM. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (239.1 mM), Sonication is recommended. H2O : 35 mg/mL (167.37 mM), Sonication is recommended. Ethanol : 1 mg/mL (4.78 mM), Sonication is recommended. |
| Keywords | schizophrenia | Rheumatoid | PT9 | PT 9 | Ménière | Inhibitor | inhibit | HistamineReceptor | Histamine Receptor | H3 receptor | episode | disease | CIA | Betahistine dihydrochloride | Betahistine Dihydrochloride | Betahistine | arthritis | antipsychotic |
| Inhibitors Related | Chlorphenesin | Histamine dihydrochloride | Meclizine dihydrochloride | Mirtazapine | Lidocaine | Famotidine | Mebhydrolin napadisylate | Sodium butanoate | Amitriptyline hydrochloride | Alginic acid | Trazodone hydrochloride | Mianserin hydrochloride |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | EMA Approved Drug Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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