Bax inhibitor peptide V5 NEW
| Price | $126 |
| Package | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-06 |
Product Details
| Product Name: Bax inhibitor peptide V5 | CAS No.: 579492-81-2 |
| Supply Ability: 10g | Release date: 2025/05/06 |
Product Introduction
Bioactivity
| Name | Bax inhibitor peptide V5 |
| Description | Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor exhibiting anticancer activity. |
| In vitro | Bax inhibitor peptide V5 (0-50 μM) selectively reduces cell death in STF-cMyc cells, with no significant impact on NCI-H23 or SW620 cells. It does not notably affect cell cycle arrest at the G2/M phase [1]. Furthermore, the treatment with BIPV5 leads to a substantial increase in the expression of anti-apoptotic proteins Bcl-2 and XIAP, by over 3-fold and 11-fold respectively, while concurrently decreasing the expression of pro-apoptotic proteins Bax and Bad, and the nuclear factor-κB-p65, by 10%, 30%, and nearly 50% respectively [2]. |
| In vivo | In mice model, Bax inhibitor peptide V5 (100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation [2]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 30 mg/mL (51.13 mM), Sonication is recommended. |
| Keywords | Bax inhibitor peptide V-5 | Bax inhibitor peptide V5 | Bax |
| Inhibitors Related | Gossypol (acetic acid) | (S)-(+)-Ibuprofen | Allethrin | Navitoclax | Gossypol | Diphenyl disulfide | Triacetylresveratrol | Lisaftoclax | UMI-77 | Venetoclax | Sonrotoclax TFA | (E)-Ferulic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $44.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-05-26 | |
| $2580.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
| $6.00/50mg |
VIP3Y
|
Anko Intermational Trade Limited
|
2023-04-17 | |
| $7.00/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2020-02-18 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY