
B7-1 Protein, Cynomolgus, Recombinant (hFc) NEW
Price | $2480 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-16 |
Product Details
Product Name: B7-1 Protein, Cynomolgus, Recombinant (hFc) | Supply Ability: 10g |
Release date: 2025/07/16 |
Product Introduction
Bioactivity
Name | B7-1 Protein, Cynomolgus, Recombinant (hFc) |
Description | Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas. |
Storage | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | CD-80 | CD 80 | B-7 | B 7 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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