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Postion:Product Catalog >AZ13705339
AZ13705339
  • AZ13705339

AZ13705339 NEW

Price $39 $64 $98
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-26

Product Details

Product Name: AZ13705339 CAS No.: 2016806-57-6
Purity: 98.57% Supply Ability: 10g
Release date: 2025/07/26

Product Introduction

Bioactivity

NameAZ13705339
DescriptionAZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM. AZ13705339 binds PAK2 with a Kd of 0.32 nM. AZ13705339 can be used in studies about cancers.
In vitroAZ13705339 (300 nM) prevents Siglec-8 binding-induced eosinophil death[2]. In Namalwa cells, AZ13705339 (1 μM) inhibits αIgM-controlled but not PMA-induced adhesion[3].
In vivoIn rats, AZ13705339 (100 mg/kg, p.o.) exhibits moderate clearance and Cmax of 7.7 μM[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 225 mg/mL (357.3 mM), Sonication is recommended.
KeywordsPAK1 | AZ13705339
Inhibitors RelatedFingolimod hydrochloride | ZINC194100678 | PIR 3.5 | PF-3758309 hydrochloride | G-5555 | FRAX1036 | FRAX597 | NVS-PAK1-1 | GNE 2861 | 5-Aminosalicylic Acid | Fingolimod | FRAX486 HCL(1232030-35-1 free base)
Related Compound LibrariesBioactive Compound Library | Kinase Inhibitor Library | Inhibitor Library | Bioactive Compounds Library Max | Fluorochemical Library | Covalent Inhibitor Library | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$1280.00/100mg
VIP1Y
TargetMol Chemicals Inc.
2025-04-30
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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