Atomoxetine NEW
| Price | $1520 |
| Package | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-22 |
Product Details
| Product Name: Atomoxetine | CAS No.: 83015-26-3 |
| Supply Ability: 10g | Release date: 2025/06/22 |
Product Introduction
Bioactivity
| Name | Atomoxetine |
| Description | Atomoxetine (HSDB 7352) is a selective norepinephrine inhibitor that may cause an increase in blood pressure by increasing norepinephrine concentrations in peripheral sympathetic neurons .Atomoxetine is a highly selective antagonist of presynaptic norepinephrine transporters with little or no affinity for other norepinephrine receptors or other neurotransmitter transporters or receptors, but has little or no affinity for 5- hydroxytryptamine transporter. Atomoxetine selectively inhibits reuptake of norepinephrine and can be used to treat adolescents with ADHD and chronic tics. |
| In vitro | Atomoxetine (Tomoxetine) exhibits state- and dose-dependent interaction with the human cardiac sodium channel (hNav1.5) in tsA201 cells, with concentrations ranging from 1 to 100 μM and exposure durations of 0.5 to 20 seconds.[2] |
| In vivo | Administration of Atomoxetine (Tomoxetine) at doses of 0.3-3 mg/kg (i.p.) for a duration of 0-4 hours in male Sprague-Dawley rats results in a threefold increase in extracellular norepinephrine and dopamine levels, along with an increase in Fos expression observed in the prefrontal cortex.[1] Furthermore, Atomoxetine (Tomoxetine) at doses of 0.1-5 mg/kg (i.p. and p.o.) administered over a period of 14 days in spontaneously hypertensive rats demonstrates the potential to ameliorate ADHD-related behaviors in rats.[3] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
| Solubility Information | DMSO : Soluble |
| Keywords | norepinephrine transporter (NET) | Norepinephrine (NE) | Atomoxetine |
| Inhibitors Related | Nortriptyline hydrochloride | Ziprasidone hydrochloride | Diosmin | Escitalopram | Desvenlafaxine succinate hydrate | Ziprasidone hydrochloride monohydrate | Atomoxetine hydrochloride | Desvenlafaxine | Amitriptyline hydrochloride | Dextromilnacipran | Milnacipran hydrochloride | Doxepin hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1.00/1kg |
VIP1Y
|
S&Y Biochem Co.,Ltd
|
2024-10-14 | |
| $0.00/25Kg/Bag |
Sinoway Industrial co., ltd.
|
2021-07-21 | ||
| $0.00/25kg |
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
|
2024-05-17 | ||
| $0.00/1KG |
VIP3Y
|
Henan Aochuang Chemical Co.,Ltd.
|
2022-10-13 | |
| $2.00/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2020-01-07 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY