Apamin acetate NEW
| Price | $110 | $248 | $358 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-09 |
Product Details
| Product Name: Apamin acetate | Purity: 96.97% |
| Supply Ability: 10g | Release date: 2025/07/09 |
Product Introduction
Bioactivity
| Name | Apamin acetate |
| Description | Apamin acetate (Apamine acetate) is a selective Ca2+-activated blocker of K+ (SK) channels, an 18-amino acid peptide neurotoxin found in bee toxins.Apamin acetate enhances synapse growth and regeneration following laceration injury to cortical neurons.Apamin acetate has anti-inflammatory and anti-fibrotic effects. |
| In vitro | Apamin acetate (0.5-2 μg/mL; 24 h; HSC-T6 cells) treatment effectively diminishes α-SMA expression in TGF-β1-induced HSC-T6 cells. Furthermore, Apamin acetate treatment prevents the activation of p-Smad2/3 and Smad4 induced by TGF-β1.[1] |
| In vivo | Apamin acetate (0.1 mg/kg; i.p.; twice a week; for 4 weeks; C57BL/6 male mice) leads to reduced liver injury and lowered proinflammatory cytokine levels. Additionally, it inhibits collagen deposition, bile duct epithelial cell (BEC) proliferation, and the expression of fibrogenic genes in DDC-fed mice.[1] |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | PotassiumChannel | Potassium Channel | Apamine Acetate | Apamin Acetate |
| Inhibitors Related | Minoxidil sulfate | Tannic acid | Cromolyn sodium | Hydrochlorothiazide | (±)-Naringenin | Halothane | Tetraethylammonium chloride | Ursodeoxycholic acid | Cloperastine hydrochloride | Chlorzoxazone | Nifedipine | Indapamide |
| Related Compound Libraries | Peptide Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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