Anamorelin Fumarate NEW
| Price | $1670 | $2180 | $2800 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-18 |
Product Details
| Product Name: Anamorelin Fumarate | CAS No.: 339539-92-3 |
| Supply Ability: 10g | Release date: 2025/07/18 |
Product Introduction
Bioactivity
| Name | Anamorelin Fumarate |
| Description | Anamorelin Fumarate is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay). |
| In vitro | No significant antagonist activity is observed with Anamorelin at concentrations of up to 1,000 nM. In the binding experiments, Anamorelin binds to the ghrelin receptor with a binding affinity constant (Ki) of 0.70 nM. In the competition assay with radiolabeled ibutamoren (another ghrelin receptor agonist), Anamorelin is also found to bind with high affinity to the ghrelin receptor (IC50: 0.69 nM). In rat pituitary cells incubated with Anamorelin, there is a dose-dependent stimulatory effect on GH release and the potency (EC50) is 1.5 nM. Anamorelin is screened for activity against a set of over 100 receptors, ion channels, transporters, and enzymes. Anamorelin demonstrates binding to the tachykinin neurokinin 2 (NK2) site (IC50: 0.021 μM); however, a subsequent NK2 functional assay demonstrates no functional activity. |
| In vivo | In rats, oral administration of Anamorelin at doses of 3, 10, or 30 mg/kg once daily significantly enhanced food intake and body weight from Day 2 to Day 7 of treatment, compared to the vehicle control. The observed increases in food consumption and weight gain were dose-dependent and statistically significant across all dosage levels when compared to the control group. Additionally, a single oral dose of Anamorelin at 3, 10, or 30 mg/kg resulted in a dose-dependent elevation in plasma GH levels and GH AUC0-6h. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | RC-1291 Fumarate | RC 1291 Fumarate | ONO7643 Fumarate | ONO 7643 Fumarate | ghrelin receptor | Anamorelin Fumarate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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