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Postion:Product Catalog >Amyloid Precursor Protein, Human, Recombinant (hFc)
Amyloid Precursor Protein, Human, Recombinant (hFc)
  • Amyloid Precursor Protein, Human, Recombinant (hFc)

Amyloid Precursor Protein, Human, Recombinant (hFc) NEW

Price $4200
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-16

Product Details

Product Name: Amyloid Precursor Protein, Human, Recombinant (hFc) Supply Ability: 10g
Release date: 2025/07/16

Product Introduction

Bioactivity

NameAmyloid Precursor Protein, Human, Recombinant (hFc)
DescriptionAmyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective processing through the amyloidogenic pathway. Human APP695 consists of a 17 amino acid (aa) signal sequence, a 607 aa extracellular domain (ECD), a 24 aa transmembrane domain, and a 47 aa cytoplasmic domain. Within the ECD, human APP695 shares 97% aa sequence identity with mouse and rat APP695. Amyloid beta is a major molecule implicated in pathogenesis of Alzheimer's disease (AD) and related dementias. AICD regulates expression by direct promoter binding of multiple genes, including APP itself, the beta-secretase, BACE-1 and the Amyloid beta-degrading enzyme, Neprilysin. As such, APP695 plays an important role in brain development, learning and memory, synaptic plasticity, and neurodegeneration including AD.
StorageShipping with blue ice/Shipping at ambient temperature.
KeywordsAPP-695 | APP 695

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

Product name Price   Suppliers Update time
$57.00/100μg
VIP5Y
TargetMol Chemicals Inc.
2025-07-16
$7960.00/1mg
VIP1Y
TargetMol Chemicals Inc.
2025-06-24
$0.10/1kg
VIP3Y
Zibo Hangyu Biotechnology Development Co., Ltd
2024-01-09
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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