ADRA1D receptor antagonist 1 HCl NEW
| Price | $199 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: ADRA1D receptor antagonist 1 HCl | CAS No.: 1191908-14-1 |
| Purity: 98.13% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | ADRA1D receptor antagonist 1 HCl |
| Description | ADRA1D receptor antagonist 1 HCl is an orally active, potent and selective α1D adrenergic receptor antagonist (Ki: 1.6 nM) with potential antiproliferative activity. |
| Animal Research | Animal Model: Rat with bladder outlet obstruction (BOO). Dosage: 4.4 μg/kg. Administration: Intravenous injection |
| In vitro | ADRA1D receptor antagonist 1 exhibits low hERG inhibition and higher selectivity for α1D-AR over α1A- and α1B-ARs, without affecting α1A- and α1B-ARs[1]. |
| In vivo | In the rat model of bladder outlet obstruction (BOO), ADRA1D receptor antagonist 1 (4.4 μg/kg; intravenous injection) dose-dependently decreased the occurrence of non-voiding bladder contractions during the urinary storage phase[1]. |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 80 mg/mL (237.25 mM), Sonication is recommended. |
| Keywords | α1D-adrenergic receptor | α1D adrenoceptor | AdrenergicReceptor | Adrenergic Receptor | ADRA-1D receptor antagonist 1 | ADRA1D receptor antagonist 1 |
| Inhibitors Related | Olanzapine | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Dexmedetomidine hydrochloride | Phenylephrine hydrochloride | Amitriptyline hydrochloride | Isoprenaline hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride | Doxepin hydrochloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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