Product Details
| Product Name:
ACH-806 |
CAS No.:
870142-71-5 |
| Supply Ability:
10g |
Release date:
2025/07/22 |
Product Introduction
Bioactivity
| Name | ACH-806 |
| Description | ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM. |
| In vitro | ACH-806, an NS4A antagonist, effectively hinders the replication of the Hepatitis C Virus (HCV) with an EC50 value of 14 nM. Treatment with ACH-806 notably decreases the immunoprecipitation levels of labeled NS3 and NS4A by anti-NS3 antibody. It significantly reduces NS3 and NS4A levels and facilitates p14 formation in original replicon cells, albeit not affecting ACH-806-resistant cells[1]. Moreover, ACH-806 administration leads to notable reductions in NS3 and NS4A within transfected cells, mirroring effects observed in replicon cells treated with the compound, where both NS3 and NS4A levels decrease significantly. Following ACH-806 treatment, NS3 amounts are diminished approximately 6-fold (100/16), and NS4A-bound NS3 is reduced roughly 29-fold (261/9). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | HCVProtease | HCV Protease | HCV | GS-9132 | GS 9132 | ACH-806 | ACH806 | ACH 806 |
| Inhibitors Related | EIDD-1931 | AG-1478 | Methyl 2-amino-5-bromobenzoate | RO8191 | Ribavirin | Sofosbuvir | Deferiprone | Ombitasvir | Artemisinin | HCV-IN-29 | Honokiol | Resiquimod |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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