Product Details
Product Name:
ACBI1 |
CAS No.:
2375564-55-7 |
Purity:
98.15% |
Supply Ability:
10g |
Release date:
2025/07/25 |
Product Introduction
Bioactivity
Name | ACBI1 |
Description | ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO : 100 mg/mL (106.83 mM), Sonication is recommended.
|
Keywords | PROTACs | PROTAC | Inhibitor | inhibit | EpigeneticReaderDomain | Epigenetic Reader Domain | DC50: 6 nM (SMARCA2), 11 nM (SMARCA4), 32 nM (PBRM1) | Apoptosis | anti-proliferative | ACBI-1 | ACBI1 | ACBI 1 |
Inhibitors Related | Stavudine | 5-Fluorouracil | Flubendazole | Cysteamine hydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | Curcumin | L-Ascorbic acid sodium salt | Alginic acid |
Related Compound Libraries | Histone Modification Compound Library | Bioactive Compound Library | Ubiquitination Compound Library | Epigenetics Compound Library | NO PAINS Compound Library | PPI Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
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Price |
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Suppliers |
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$200.00/100MG |
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Hubei Chuchang Biotech Co., Ltd.
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2024-11-18 |
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