Abeprazan hydrochloride NEW
| Price | $56 | $143 | $212 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-21 |
Product Details
| Product Name: Abeprazan hydrochloride | CAS No.: 1902954-87-3 |
| Purity: 98.62% | Supply Ability: 10g |
| Release date: 2025/05/21 |
Product Introduction
Bioactivity
| Name | Abeprazan hydrochloride |
| Description | Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activation. Abeprazan hydrochloride is a proton pump inhibitor (PPI) that acts by reducing gastric acid production and is used to treat gastric acid-related disorders, such as gastroesophageal reflux disease (GERD) and peptic ulcers. |
| In vitro | The mechanism of action of Abeprazan hydrochloride involves reversible binding to H+, K+-ATPase, and, unlike PPIs, it does not require an acidic environment for activation [1]. |
| In vivo | Abeprazan hydrochloride effectively suppresses acid secretion in a dose-responsive manner, demonstrating equal or superior efficacy to vonoprazan, an established P-CAB, across multiple in vivo studies including pylorus-ligated rats, lumen-perfused rat models, and Heidenhain pouch dog models[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 40 mg/mL (89.51 mM), Sonication is recommended. |
| Keywords | Protonpump | Proton pump | Fexuprazan Hydrochloride | DWP-14012 Hydrochloride | DWP14012 Hydrochloride | DWP 14012 Hydrochloride | Abeprazan Hydrochloride |
| Inhibitors Related | Ilaprazole | Omeprazole Sodium | Chebulinic acid | Esomeprazole | Pantoprazole sodium | Esomeprazole Magnesium | Pantoprazole Sodium Hydrate | Vonoprazan Fumarate | Lansoprazole | Zinc pyrithione | Esomeprazole Sodium | Pantoprazole |
| Related Compound Libraries | Exosome Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
Recommended supplier
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| $56.00/1mg |
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2025-03-25 | |
| $0.00/1g |
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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