
7-Ethylcamptothecin NEW
Price | Get Latest Price |
Package | 1kg |
Min. Order: | 1kg |
Supply Ability: | 1000kg |
Update Time: | 2025-08-01 |
Product Details
Product Name: 7-Ethylcamptothecin | CAS No.: 78287-27-1 |
Min. Order: 1kg | Purity: 0.99 |
Supply Ability: 1000kg | Release date: 2025/08/01 |
7-Ethylcamptothecin - Product Introduction
Definition: 7-Ethylcamptothecin is a derivative of camptothecin, a naturally occurring alkaloid with potent anticancer properties. It is a topoisomerase I inhibitor that induces DNA damage and promotes apoptosis (programmed cell death) in cancer cells.
Functions:
· Inhibits the enzyme topoisomerase I, which is essential for DNA replication and transcription, leading to DNA breaks and cancer cell death.
· Shows strong cytotoxic activity against various types of cancer cells, particularly those in solid tumors.
· Effective in halting tumor growth and preventing metastasis by disrupting cellular processes.
Applications:
· Pharmaceutical Industry: Used as an intermediate in the synthesis of anticancer drugs like irinotecan and topotecan, which are part of chemotherapy regimens.
· Healthcare: Investigated for its potential use in treating solid tumors, including ovarian, colon, and lung cancer, often as part of combination therapies.
· Research: Studied in preclinical and clinical trials to evaluate its effectiveness in treating resistant cancers and to optimize its formulation for better therapeutic outcomes.
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