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Postion:Product Catalog >7-Chlorokynurenic acid
7-Chlorokynurenic acid
  • 7-Chlorokynurenic acid

7-Chlorokynurenic acid NEW

Price $61 $128 $245
Package 10mg 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-06-22

Product Details

Product Name: 7-Chlorokynurenic acid CAS No.: 18000-24-3
Purity: 99.72% Supply Ability: 10g
Release date: 2025/06/22

Product Introduction

Bioactivity

Name7-Chlorokynurenic acid
Description7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
In vivoIn male Sprague-Dawley rats, 7-Chlorokynurenic acid (10 nM) retardates the development of both the electroencephalographic and motor (17.7 daily stimulations) components of the seizure response[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.
Solubility InformationDMSO : 15 mg/mL (67.1 mM), Sonication is recommended.
Keywordsreuptake of glutamate | NMDA receptor | Glycine B coagonist site of NMDA receptor | Glutamate receptor | 7-Chlorokynurenic acid
Inhibitors RelatedMephenesin | Urethane | Decanoic Acid | Halothane | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Riluzole | D-Serine | O-Phospho-L-serine | Procaine hydrochloride
Related Compound LibrariesMarine Natural Product Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Natural Product Library | Anti-Viral Compound Library | Inhibitor Library | Neuroprotective Compound Library | Microbial Natural Product Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Ion Channel Targeted Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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