
7-Chlorokynurenic acid NEW
Price | $61 | $128 | $245 |
Package | 10mg | 25mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-06-22 |
Product Details
Product Name: 7-Chlorokynurenic acid | CAS No.: 18000-24-3 |
Purity: 99.72% | Supply Ability: 10g |
Release date: 2025/06/22 |
Product Introduction
Bioactivity
Name | 7-Chlorokynurenic acid |
Description | 7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery. |
In vivo | In male Sprague-Dawley rats, 7-Chlorokynurenic acid (10 nM) retardates the development of both the electroencephalographic and motor (17.7 daily stimulations) components of the seizure response[3]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
Solubility Information | DMSO : 15 mg/mL (67.1 mM), Sonication is recommended. |
Keywords | reuptake of glutamate | NMDA receptor | Glycine B coagonist site of NMDA receptor | Glutamate receptor | 7-Chlorokynurenic acid |
Inhibitors Related | Mephenesin | Urethane | Decanoic Acid | Halothane | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Riluzole | D-Serine | O-Phospho-L-serine | Procaine hydrochloride |
Related Compound Libraries | Marine Natural Product Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Natural Product Library | Anti-Viral Compound Library | Inhibitor Library | Neuroprotective Compound Library | Microbial Natural Product Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Ion Channel Targeted Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$44.00/2mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2025-07-18 | |
$3.00/50kg |
VIP1Y
|
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
|
2025-07-28 | |
$61.00/10mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2025-06-21 | |
$61.00/10mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-05-26 |
- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY