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Postion:Product Catalog >Inorganic chemistry>Inorganic salts>Metal nitrates and nitrites>Trilostane
Trilostane
  • Trilostane

Trilostane

Price $1
Package 1g
Min. Order: 1g
Supply Ability: 2000 Kilogram/Kilograms per Month
Update Time: 2019-07-31

Product Details

Product Name: Trilostane CAS No.: 13647-35-3
EC-No.: 237-133-0 Min. Order: 1g
Purity: 99% Supply Ability: 2000 Kilogram/Kilograms per Month
Release date: 2019/07/31

Product name

Trilostane

CAS No

13647-35-3

Molecular formula

C20H27NO3

Molecular Weight

289.3495

Amino Acid Composition:

10% of theoretical

Type:

Powder

Apperance:

white powder

Assay

99%

MOQ

10G

 

Details  :   

Product name:Trilostane

Synonym: Veto r,yl

CAS Registry Number:13647-35-3

Alias:99%

Einecs No:237-133-0

Grade : Pharmaceutical Grade

Storage: Shading, confined preservation

Appearance:White crystalline powder

Usage : Trilostane can inhibit cortical hormones in the process of synthesis of 3 beta dehydrogenase, make the cortis.ol, aldoster.one synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolis.m) and primary aldosteronis.m. This product also had significantly effect to decreased serum level.

Application

Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.

Trilostane blocks an enzyme involved in the production of several steroids including cortiso l. Inhibiting this enzyme inhibits the production of cortis ol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.

Trilostane produces suppression of the adrenal cortex by inhibiting enzyma tic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroidisomerase, thus blocking synthesis of adrenal steroids.

Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.

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