4-Aminoantipyrine

Modify Date: 2024-01-02 16:21:27

4-Aminoantipyrine structure	Common Name	4-Aminoantipyrine
	CAS Number	83-07-8	Molecular Weight	203.240
	Density	1.2±0.1 g/cm3	Boiling Point	309.0±45.0 °C at 760 mmHg
	Molecular Formula	C11H13N3O	Melting Point	105-110 °C(lit.)
	MSDS	ChineseUSA	Flash Point	140.7±28.7 °C
	Symbol	GHS07	Signal Word	Warning

Purity		Quantity		Budget		Inquiry

Use of 4-Aminoantipyrine Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol.

• Properties

• Articles46

• Spectrum

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 Names

Name	4-aminoantipyrine
Synonym	More Synonyms

 4-Aminoantipyrine Biological Activity

Description	Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol.
Related Catalog	Research Areas >> Others
Target	COX
References	[1]. Berno CR, et al. 4-Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24.

 Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	309.0±45.0 °C at 760 mmHg
Melting Point	105-110 °C(lit.)
Molecular Formula	C11H13N3O
Molecular Weight	203.240
Flash Point	140.7±28.7 °C
Exact Mass	203.105865
PSA	52.95000
LogP	-0.40
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.607
Storage condition	Store at RT.
Stability	Stable. May be light sensitive.
Water Solubility	ca. 500 g/L (20 oC)

 MSDS

4-Aminoantipyrine MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION RTECS NUMBER : CD2480000 CHEMICAL NAME : Antipyrine, 4-amino- CAS REGISTRY NUMBER : 83-07-8 BEILSTEIN REFERENCE NO. : 0181635 LAST UPDATED : 199710 DATA ITEMS CITED : 11 MOLECULAR FORMULA : C11-H13-N3-O MOLECULAR WEIGHT : 203.27 WISWESSER LINE NOTATION : T5NNVJ A1 BR& DZ E1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 270 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - excitement MUTATION DATA TYPE OF TEST : DNA repair TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 312 ug/well REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 133,161,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82277 No. of Facilities: 114 (estimated) No. of Industries: 4 No. of Occupations: 3 No. of Employees: 1130 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82277 No. of Facilities: 1080 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 12808 (estimated) No. of Female Employees: 9012 (estimated)

 Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36-S36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	CD2480000
HS Code	29331190

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