3-Bromo-7-nitroindazole NEW
| Price | $46 | $76 | $189 |
| Package | 50mg | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: 3-Bromo-7-nitroindazole | CAS No.: 74209-34-0 |
| Purity: 97.44% | Supply Ability: 10g |
| Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | 3-Bromo-7-nitroindazole |
| Description | 3-Bromo-7-nitroindazole is a specific neuronal nitric oxide synthase (nNOS) inhibitor that affects the synthesis of the intercellular messenger NO throughout the brain and body. |
| In vivo | Male rats received either 3-Bromo-7-nitroindazole (20mg/kg/day) or saline via intraperitoneal injection for 5days. Daily administration of the specific neuronal nitric oxide synthase (nNOS) inhibitor, 3-Bromo-7-nitroindazole impaired the acquisition of the Morris water maze (MWM) paradigm task. 3-Bromo-7-nitroindazole also impaired the probe trial. The MWM training was associated with a significant increase in the brain-derived neurotrophic factor (BDNF) mRNA expression in the hippocampus. BDNF mRNA expression in the hippocampus did not change after 3-Bromo-7-nitroindazole treatment. L-arginine significantly reversed behavioural parameters, and the effect of 3-Bromo-7-nitroindazole was found to be NO-dependent. There were no differences in locomotor activity and blood pressure in 3-Bromo-7-nitroindazole treated rats[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 100 mg/mL (413.17 mM), Sonication is recommended. |
| Keywords | NOS | NO Synthase | nNOS | Nitric oxide synthases | Inhibitor | inhibit | 3-Bromo-7-nitroindazole | 3Bromo7nitroindazole | 3 Bromo 7 nitroindazole |
| Inhibitors Related | Miconazole | MSU-42011 | Aminoguanidine hydrochloride | L-NAME hydrochloride | EIT hydrobromide | Dexamethasone acetate | S-Methylisothiourea sulfate | Cannabigerol | 1400W dihydrochloride | Flavone | S-(2-aminoethyl) Isothiourea (dihydrobromide) | Diallyl disulfide |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Neuroprotective Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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