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Postion:Product Catalog >(1R,2R)-ML-SI3
(1R,2R)-ML-SI3
  • (1R,2R)-ML-SI3

(1R,2R)-ML-SI3 NEW

Price $233 $1110 $1450
Package 2mg 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-06-05

Product Details

Product Name: (1R,2R)-ML-SI3 CAS No.: 2418594-00-8
Supply Ability: 10g Release date: 2025/06/05

Product Introduction

Bioactivity

Name(1R,2R)-ML-SI3
Description(1R,2R)-ML-SI3 ((-)-trans-ML-SI3) is a selective TRPML1, TRPML2, and TRPML3 inhibitor for the study of neurodegenerative and cardiovascular diseases.
In vitro(1R,2R)-ML-SI3 is an isomer of ML-SI3 and a potent inhibitor of all three TRPML isoforms. (1R,2R)-ML-SI3 was a potent inhibitor of TRPML1 (IC50=1.6 μM), TRPML2 (IC50=2.3 μM) and TRPML3 (IC50=12.5 μM), (1R,2R)-ML-SI3 was a potent inhibitor of TRPML1 and TRPML2 and a weak inhibitor of TRPML3. [1]
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 80 mg/mL(186.23 mM), Sonication is recommended.
KeywordsTRPML

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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