A kind of intestinal antibiotic, is a rifamycin derivative, suitable for Gellanid positive and negative bacteria, aerobic and anaerobic bacteria caused by acute and chronic intestinal infections, diarrhea syndrome, Chemicalbook intestinal flora caused by changes in diarrhea, preoperative and postoperative intestinal prophylaxis, hyperamination, portal venous shunt encephalitis, liver coma. It is a highly effective and low toxicity intestinal antibiotic.