Product Details
| Product Name:
(-)-Anonaine |
CAS No.:
1862-41-5 |
| Purity:
99.66% |
Supply Ability:
10g |
| Release date:
2025/07/15 |
Product Introduction
Bioactivity
| Name | (-)-Anonaine |
| Description | (-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antidepressant and vasodilatory activities. (-)-Anonaine induces apoptosis in human cervical cancer (HeLa) cells, induces DNA damage and inhibits the growth and migration of human lung cancer h1299 cells through Bax and caspase-dependent pathways. |
| In vitro | (-)-Anonaine (50-200 μM ; 24h ; ) exhibited significant inhibition to cell growth and migration activities on human lung cancer H1299 cells.[1]
(-)-Anonaine (10-200 μM) significant nuclear damages of H1299 cells were observed treatment in a comet assay, whereas higher concentrations (6 and 30 mM) of (-)-anonaine concentrations were required to cause DNA damages in an in vitro plasmid cleavage assay.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 2.65 mg/mL (9.99 mM), Sonication is recommended.
|
| Keywords | p53 | P. falciparum | Fungal | Caspase | Bcl-2 | Apoptosis | Antioxidant | Anonaine | ()Anonaine | ( ) Anonaine |
| Inhibitors Related | Stavudine | Dehydroacetic acid sodium | Cysteamine hydrochloride | Kojic acid | Sodium 4-phenylbutyrate | Terbinafine hydrochloride | Hydroxychloroquine | Doxycycline | Tributyrin | Geraniol | L-Ascorbic acid sodium salt | Alginic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Anti-Parasitic Compound Library | Traditional Chinese Medicine Monomer Library | Alkaloid Natural Product Library | Anti-Fungal Compound Library | Miao medicine Compound Library | Antiparasitic Natural Product Library | Natural Product Library for HTS | Anti-Aging Compound Library | Anti-infective Natural Product Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Ancient Chinese Classical Formulas Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States