| Company Name: |
Artis Biotech Co. Ltd.
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| Tel: |
028-67271278 18582380095 |
| Email: |
sales@artisbio.com |
| Products Intro: |
Product Name:Imatinib D4
CAS:1134803-16-9
Purity:99% HPLC Package:1mg 5mg 10mg 50mg 100mg
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[2H4]-Imatinib manufacturers
- Imatinib D4
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- $197.00 / 1mg
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2024-10-24
- CAS:1134803-16-9
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | [2H4]-Imatinib Basic information |
| Product Name: | [2H4]-Imatinib | | Synonyms: | [2H4]-Imatinib;CGP-57148B D4;STI571 D4;Imatinib D4Q: What is
Imatinib D4 Q: What is the CAS Number of
Imatinib D4 Q: What is the storage condition of
Imatinib D4 Q: What are the applications of
Imatinib D4;N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide-2,3,5,6-d4;N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl](2H?)benzamide | | CAS: | 1134803-16-9 | | MF: | C29H31N7O | | MW: | 493.62 | | EINECS: | | | Product Categories: | | | Mol File: | 1134803-16-9.mol | ![[2H4]-Imatinib Structure](CAS/20211123/GIF/1134803-16-9.gif) |
| | [2H4]-Imatinib Chemical Properties |
| storage temp. | Store at -20°C | | form | Solid | | color | Off-white to light yellow |
| | [2H4]-Imatinib Usage And Synthesis |
| Uses | Imatinib-d4 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2]. | | References | [1] Heinrich MC, et al. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood. 2000 Aug 1;96(3):925-32. PMID:10910906
[2] Guida T, et al. Sorafenib inhibits imatinib-resistant KIT and platelet-derived growth factor receptor beta gatekeeper mutants. Clin Cancer Res. 2007 Jun 1;13(11):3363-9. DOI:10.1158/1078-0432.CCR-06-2667
[3] Coleman CM, et al, Frieman MB. Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion. J Virol. 2016;90(19):8924‐8933. Published 2016 Sep 12. DOI:10.1128/JVI.01429-16 |
| | [2H4]-Imatinib Preparation Products And Raw materials |
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