| Company Name: |
Shanghai EFE Biological Technology Co., Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
info@efebio.com |
| Products Intro: |
Product Name:[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate
CAS:1064-06-8
Purity:95% Package:1mg;2mg;5mg
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QUERCETINPENTAACETATE manufacturers
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| | QUERCETINPENTAACETATE Basic information |
| Product Name: | QUERCETINPENTAACETATE | | Synonyms: | 3,3',4',5,7-Penta(acetyloxy)flavone;3,3',4',5,7-Pentaacetoxyflavone;Quercetin acetate;Quercetine pentaacetate;3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one;Pentaacetylquercetin;[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate;4H-1-Benzopyran-4-one, 3,5,7-tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]- | | CAS: | 1064-06-8 | | MF: | C25H20O12 | | MW: | 512.42 | | EINECS: | | | Product Categories: | | | Mol File: | 1064-06-8.mol |  |
| | QUERCETINPENTAACETATE Chemical Properties |
| Melting point | 193 °C | | Boiling point | 666.4±55.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Dichloromethane, Ethyl Acetate | | form | Solid | | color | Beige |
| | QUERCETINPENTAACETATE Usage And Synthesis |
| Description | Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively). | | Uses | [5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. |
| | QUERCETINPENTAACETATE Preparation Products And Raw materials |
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