| Company Name: |
Suzhou Meishi Biotechnology Co., Ltd.
|
| Tel: |
1173954148q |
| Email: |
meishipharma@126.com |
| Products Intro: |
Product Name:181238-67-5
CAS:181238-67-5
Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:MCC-134
CAS:181238-67-5
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
|
Cyclobutanecarbothioamide, 1-[4-(1H-imidazol-1-yl)benzoyl]-N-methyl- manufacturers
- MCC-134
-
- $1980.00 / 50mg
-
2024-10-28
- CAS:181238-67-5
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Cyclobutanecarbothioamide, 1-[4-(1H-imidazol-1-yl)benzoyl]-N-methyl- Basic information |
| | Cyclobutanecarbothioamide, 1-[4-(1H-imidazol-1-yl)benzoyl]-N-methyl- Chemical Properties |
| Boiling point | 491.3±55.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | pka | 12.24±0.20(Predicted) |
| | Cyclobutanecarbothioamide, 1-[4-(1H-imidazol-1-yl)benzoyl]-N-methyl- Usage And Synthesis |
| Description | MCC-134 is an inverse agonist for the pancreatic-type ATP-sensitive K(+) channel as vascular relaxing agent. | | Uses | MCC-134, a blocker of mitochondrial and opener of surface ATP-sensitive K+ (KATP) channels, abrogates cardioprotective effects of chronic hypoxia. MCC-134 is a vasorelaxing agent[1][2]. | | References | [1] F Kolár, et al. MCC-134, a blocker of mitochondrial and opener of sarcolemmal ATP-sensitive K+ channels, abrogates cardioprotective effects of chronic hypoxia. Physiol Res. 2005;54(4):467-71. PMID:16117602
[2] Norihito Sasaki, et al. MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning. Circulation. 2003 Mar 4;107(8):1183-8. DOI:10.1161/01.cir.0000051457.64240.63 |
| | Cyclobutanecarbothioamide, 1-[4-(1H-imidazol-1-yl)benzoyl]-N-methyl- Preparation Products And Raw materials |
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