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1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1)

1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1) Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:SKF-83566 hydrobromide
CAS:108179-91-5
Package:10mg;240USD|5mg;155USD|25mg;485USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:SKF 83566 hydrobromide
CAS:108179-91-5
Purity:95% Package:$71.9/5mg;$109.9/10mg;Bulk package Remarks:95%
Company Name: Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.  
Tel: 025-66099280 17798518460
Email: cfzhang@aikonchem.com
Products Intro: Product Name:SKF83566HG
CAS:108179-91-5
Purity:95% Package:1g;5g;10g
Company Name: Shanghai Aladdin Bio-Chem Technology Co.,LTD  
Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Products Intro: Product Name:SKF 83566 hydrobromide
CAS:108179-91-5
Purity:95% Package:10mg/RMB 1544.90;50mg/RMB 1980.00;5mg/RMB 926.90
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
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Products Intro: Product Name:SKF83566
CAS:108179-91-5
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G

1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1) manufacturers
1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1) Basic information
Product Name:1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1)
Synonyms:1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1);SKF83566HG;8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol:hydrobromide;1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1;113762;8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrobromide;CS-2574;SKF 83566 hydrobromide, D1 receptor antagonist (DMSO solution)
CAS:108179-91-5
MF:C17H19Br2NO
MW:413.15
EINECS:
Product Categories:
Mol File:108179-91-5.mol
1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1) Structure
1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1) Chemical Properties
storage temp. Desiccate at RT
solubility Soluble to 5 mM in water with gentle warming and to 100 mM in DMSO
form Powder
Safety Information
MSDS Information
1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1) Usage And Synthesis
UsesSKF 83566 Hydrobromide is a very potent and selective D1-like dopamine receptor antagonist, specifically at the 5-HT2 receptor.
in vivo

SKF 83566 hydrobromide (oral administration; 20 μg/mL; 7 days) alone has no effects on altering LTP (115%). However, combinnation of SKF 83566 and nicotine significantly blocks the enhancement of long-term synaptic potentiation (LTP) induced by pretreatment with nicotine (SKF 83566+nicotine+cocaine, 120%; nicotine+cocaine, 143%)[1].

Animal Model:Male C57BL6/J mice (6- to 9-wk-old)[1]
Dosage:20 μg/mL (Together with nicotine for 7 d, followed by the injection of cocaine)
Administration:Oral administration; 7 days
Result:Blocked nicotine and cocaine-induced facilitation of LTP.
IC 50D1 Receptor; D5 Receptor; 5-HT2 Receptor: 11 nM (Ki)
storageroom temperature (desiccate)
1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1) Preparation Products And Raw materials
Tag:1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1)(108179-91-5) Related Product Information
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