NH-bis(C1-PEG1-Boc) manufacturers
- NH-bis(C1-PEG1-Boc)
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- $77.00 / 5mg
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2024-10-28
- CAS:2171072-53-8
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | NH-bis(C1-PEG1-Boc) Basic information |
| Product Name: | NH-bis(C1-PEG1-Boc) | | Synonyms: | NH-bis(C1-PEG1-Boc);2-Amino-1,3-bis(t-butoxycarbonylethoxy)propane;di-tert-butyl 3,3'-((2-aminopropane-1,3-diyl)bis(oxy))dipropionate;Propanoic acid, 3,3'-[(2-amino-1,3-propanediyl)bis(oxy)]bis-, 1,1'-bis(1,1-dimethylethyl) ester;NH-bis(CH2-PEG1-Boc) | | CAS: | 2171072-53-8 | | MF: | C17H33NO6 | | MW: | 347.45 | | EINECS: | | | Product Categories: | | | Mol File: | 2171072-53-8.mol |  |
| | NH-bis(C1-PEG1-Boc) Chemical Properties |
| Boiling point | 419.0±40.0 °C(Predicted) | | density | 1.043±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, sealed storage, away from moisture and light | | solubility | Soluble in DMSO, DCM, DMF | | pka | 6.87±0.10(Predicted) | | form | Oil | | color | Colorless to light yellow |
| | NH-bis(C1-PEG1-Boc) Usage And Synthesis |
| Description | 2-Amino-1,3-bis(t-butoxycarbonylethoxy)propane is a PEG linker containing an amino group with two t-butyl esters. The amino group is reactive with carboxylic acids, activated NHS esters. The t-butyl protected carboxyl groups can be deprotected under acidic conditions. | | Uses | NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | NH-bis(C1-PEG1-Boc) Preparation Products And Raw materials |
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