| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:N1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide
CAS:218795-74-5
Purity:98% Package:1mg Remarks:S89365
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| Company Name: |
BOC Sciences
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| Tel: |
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| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:IMM 01
CAS:218795-74-5
Purity:99% Remarks:IMM 01 is an agonist of mammalian Diaphanous (mDia)-related formins that inhibits DID-DAD binding (IC50 value 140 nM).
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:IMM-01 >=98% (HPLC)
CAS:218795-74-5
Purity:NULL Package:25mg;5mg Remarks:NULL
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N1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide manufacturers
- IMM-01
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- $44.00 / 1mg
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2025-05-09
- CAS:218795-74-5
- Min. Order:
- Purity: 98.87%
- Supply Ability: 10g
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| | N1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide Basic information |
| Product Name: | N1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide | | Synonyms: | N1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide;2-[(2,4-Dihydroxyphenyl)methylene]-N-(1,1-dimethylethyl)-hydrazinecarbothioamide;IMM-01;Intramimic-01;3-tert-butyl-1-[(E)-[(2,4-dihydroxyphenyl)methylidene]amino]thiourea;IMM-01
(IMM 01);IMM-01 >=98% (HPLC);Hydrazinecarbothioamide, 2-[(2,4-dihydroxyphenyl)methylene]-N-(1,1-dimethylethyl)- | | CAS: | 218795-74-5 | | MF: | C12H17N3O2S | | MW: | 267.35 | | EINECS: | | | Product Categories: | | | Mol File: | 218795-74-5.mol |  |
| | N1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide Chemical Properties |
| Boiling point | 425.3±38.0 °C(Predicted) | | density | 1.22±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble10mg/mL, clear | | pka | 7.77±0.40(Predicted) | | form | powder | | color | white to light brown |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| | N1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide Usage And Synthesis |
| Uses | IMM-01 has been used as a formin activator to study its effects on motor neurons (MNs). | | Biological Activity | Primary Target
mDia', 'Reversible: yes | | in vivo | IMM-01 (5-25 mg/kg; i.v.; 2 times a week; for 3 weeks) is able to slow tumor growth in a mouse xenograft model of colon cancer[1]. | Animal Model: | Athymic nude female mice (6 to 8 weeks) implanted with SW480 cells[1] | | Dosage: | 5 mg/kg, 25 mg/kg | | Administration: | i.v.; 2 times a week; for 3 weeks | | Result: | Slowed tumor growth in a dose-dependent manner when administered intravenously via the tail vein.
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| | N1-(tert-butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide Preparation Products And Raw materials |
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