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Pan-RAS-IN-1

Pan-RAS-IN-1 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Pan-RAS-IN-1
CAS:1835283-94-7
Purity:98.57% Package:1mg;73USD|2mg;98USD|5mg;147USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:pan-Ras inhibitor 3144
CAS:1835283-94-7
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Products Intro: Product Name:Ras-IN-3144,Pan-RAS-IN-1
CAS:1835283-94-7
Purity:98% Package:1g;10g;100g
Company Name: Bide Pharmatech Ltd.  
Tel: 400-164-7117 13681763483
Email: product02@bidepharm.com
Products Intro: Product Name:Pan-ras-in-1
CAS:1835283-94-7
Purity:98% Package:10mg;25mg;50mg;100mg;250mg Remarks:BD00824986
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 021-61312847; 18021002903
Email: 3008007409@qq.com
Products Intro: Product Name:Pan-RAS-IN-1
CAS:1835283-94-7
Purity:>=98% Package:100mg Remarks:T24708

Pan-RAS-IN-1 manufacturers

  • Pan-RAS-IN-1
  • Pan-RAS-IN-1 pictures
  • $73.00 / 1mg
  • 2025-07-07
  • CAS:1835283-94-7
  • Min. Order:
  • Purity: 99.77%
  • Supply Ability: 10g
Pan-RAS-IN-1 Basic information
Product Name:Pan-RAS-IN-1
Synonyms:Pan-RAS-IN-1;pan-Ras inhibitor 3144;Pan-RAS inhibitor 1;4-Piperidinecarboxamide, 4-amino-N-[3-[5-[[4-[(2,6-dichlorophenyl)methyl]-1-piperazinyl]methyl]-3-[4-(trifluoromethoxy)phenyl]-1H-indol-1-yl]propyl]-;pan-Ras inhibitor 3144 (Compound 3144);Ras-IN-3144,Pan-RAS-IN-1;Ras-IN-3144;PanRASIN1,inhibit,Ras,Pan RAS IN 1,Inhibitor
CAS:1835283-94-7
MF:C36H41Cl2F3N6O2
MW:717.65
EINECS:
Product Categories:
Mol File:1835283-94-7.mol
Pan-RAS-IN-1 Structure
Pan-RAS-IN-1 Chemical Properties
Boiling point 809.7±65.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 50 mg/mL (69.67 mM)
form Solid
pka17.09±0.20(Predicted)
color White to yellow
Safety Information
MSDS Information
Pan-RAS-IN-1 Usage And Synthesis
UsesPan-RAS-IN-1 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors.
in vivo

Pan-RAS-IN-1 administration results in inhibition of tumor growth over 15 days of treatment. Pan-RAS-IN-1-treated mice exhibits decreased tumor pERK levels compared with vehicle treated mice. A modest increase in cleaved caspase-3 is also observed, showing that in this model, pan-RAS-IN-1 has the capacity to induce caspase activation[1].

References[1] Welsch ME, et al. Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 2017 Feb 23;168(5):878-889.e29. DOI:10.1016/j.cell.2017.02.006
Pan-RAS-IN-1 Preparation Products And Raw materials
Tag:Pan-RAS-IN-1(1835283-94-7) Related Product Information

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