Tos-PEG6-t-Butyl ester manufacturers
- Tos-PEG5-C2-Boc
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- $0.00 / 100mg
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2024-10-24
- CAS:850090-10-7
- Min. Order:
- Purity:
- Supply Ability: 10g
- Tos-PEG6-COOtBu
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- $0.00 / 5g
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2024-03-27
- CAS:850090-10-7
- Min. Order: 5g
- Purity: >99.00%
- Supply Ability: 5g
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| | Tos-PEG6-t-Butyl ester Basic information |
| Product Name: | Tos-PEG6-t-Butyl ester | | Synonyms: | Tos-PEG6-t-Butyl ester;Tos-PEG5-CH2CH2COOtBu;Tos-PEG5-C2-Boc;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;tert-butyl 1-(tosyloxy)-3,6,9,12,15-pentaoxaoctadecan-18-oate;3,6,9,12,15-Pentaoxaoctadecan-18-oic acid,1-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;Tos-PEG5-CH2CH2COOtBu/4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;tert-butyl 3-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate | | CAS: | 850090-10-7 | | MF: | C24H40O10S | | MW: | 520.63 | | EINECS: | | | Product Categories: | | | Mol File: | 850090-10-7.mol |  |
| | Tos-PEG6-t-Butyl ester Chemical Properties |
| form | Liquid | | color | Colorless to light yellow |
| | Tos-PEG6-t-Butyl ester Usage And Synthesis |
| Description | Tos-PEG6-t-Butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions. | | Uses | Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl/ether; PEGs | | References | [1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. |
| | Tos-PEG6-t-Butyl ester Preparation Products And Raw materials |
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