PCI-27483 manufacturers
- PCI-27483
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- $34.00 / 1mg
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2025-07-20
- CAS:871266-63-6
- Min. Order:
- Purity: 99.92%
- Supply Ability: 10g
- PCI-27483
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- $0.00 / 1g
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2020-05-17
- CAS:871266-63-6
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1kg
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| | PCI-27483 Basic information |
| Product Name: | PCI-27483 | | Synonyms: | PCI-27483;(S)-2-[[2-[5-(5-Carbamimidoyl-1H-benzimidazol-2-yl)-6,2'-dihydroxy-5'-sulfamoylbiphenyl-3-yl]acetyl]amino]succinic acid;(S)-2-(2-(5-(5-carbamimidoyl-1H-benzo[d]imidazol-2-yl)-2',6-dihydroxy-5'-sulfamoylbiphenyl-3-yl)acetamido)succinic acid;PCI27483/PCI-27483;L-Aspartic acid, N-[2-[5-[6-(aminoiminomethyl)-1H-benzimidazol-2-yl]-5'-(aminosulfonyl)-2',6-dihydroxy[1,1'-biphenyl]-3-yl]acetyl];PCI27483;PCI-27483;PCI 27483;CS-1599;PCI-27483, 10 mM in DMSO | | CAS: | 871266-63-6 | | MF: | C26H24N6O9S | | MW: | 596.57 | | EINECS: | | | Product Categories: | Pharmaceutical | | Mol File: | 871266-63-6.mol |  |
| | PCI-27483 Chemical Properties |
| density | 1.74±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:10.0(Max Conc. mg/mL);16.8(Max Conc. mM) | | form | A crystalline solid | | pka | 2.74±0.10(Predicted) | | color | Light yellow to yellow |
| | PCI-27483 Usage And Synthesis |
| Uses | PCI-27483 is a small-molecule inhibitor of activated factor VII with antineoplastic and anti-thrombotic activity. | | in vivo | PCI-27483 shows dose-dependent inhibition of thrombus formation, fibrin accumulation and PT. PCI-27483 (4 mg/kg) shows comparable anticoagulation effects as 2 mg/kg enoxaparin[1]. PCI-27483 (0 and 90 mg/kg, s.c.) results in inhibition of tumor growth in CD1 nu/nu mice implanted with BxPC3 cells[2]. |
| | PCI-27483 Preparation Products And Raw materials |
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