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| | GLYCOPROTEIN, ALPHA1-ACID HUMAN Basic information |
| Product Name: | GLYCOPROTEIN, ALPHA1-ACID HUMAN | | Synonyms: | ALPHA1-ACID GLYCOPROTEIN;ALPHA1-ACID GLYCOPROTEIN, HUMAN;ALPHA1-ACID GLYCOPROTEIN, HUMAN SERUM;ALPHA1-ACID GLYCOPROTEIN (OROSOMUCOID);ALPHA-1 ACID GLYCOPROTEIN PLASMA;ALPHA1-AG, HUMAN;ALPHA-1-SEROMUCOID, HUMAN;ALPHA1 M-SEROMUCOID, HUMAN | | CAS: | 66455-27-4 | | MF: | NULL | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![GLYCOPROTEIN, ALPHA1-ACID HUMAN Structure]() |
| | GLYCOPROTEIN, ALPHA1-ACID HUMAN Chemical Properties |
| storage temp. | 2-8°C | | solubility | H2O: 10 mg/mL, clear, colorless | | form | Lyophilized | | biological source | human plasma | | Merck | 13,8018 | | Specific Activity | 88-120nmol/min·mg |
| | GLYCOPROTEIN, ALPHA1-ACID HUMAN Usage And Synthesis |
| Uses | α1-Acid glycoprotein from human plasma has been used:
- as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers
- to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA
- to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors
| | Uses | GLYCOPROTEIN, ALPHA1-ACID HUMAN was used to study nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine. | | General Description | α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family. | | Biochem/physiol Actions | α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital. | | Purification Methods | Purify the glycoprotein 1 acid by passage through a carboxymethyl cellulose column, then through a Sephadex G-25 column. [Aronson et al. J Biol Chem 243 4564 1968.] |
| | GLYCOPROTEIN, ALPHA1-ACID HUMAN Preparation Products And Raw materials |
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