| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:HSD17B13-IN-64
CAS:2770247-34-0
Package:10mg;50mg
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| | HSD17B13-IN-64 Basic information |
| Product Name: | HSD17B13-IN-64 | | Synonyms: | HSD17B13-IN-64;Benzamide, 3,5-dichloro-N-[3-[(3-chloro-2-pyridinyl)methyl]-3,4-dihydro-4-oxo-5-quinazolinyl]-4-hydroxy- | | CAS: | 2770247-34-0 | | MF: | C21H13Cl3N4O3 | | MW: | 475.71 | | EINECS: | | | Product Categories: | | | Mol File: | 2770247-34-0.mol |  |
| | HSD17B13-IN-64 Chemical Properties |
| density | 1.580±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 5.342±0.25(predicted) |
| | HSD17B13-IN-64 Usage And Synthesis |
| Uses | HSD17B13-IN-64 (Compound 143) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-64 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1]. | | References | [1] Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28. |
| | HSD17B13-IN-64 Preparation Products And Raw materials |
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