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N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester

N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
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Products Intro: Product Name:1256490-31-9
CAS:1256490-31-9
Purity:99% Package:25KG;5KG;1KG
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Products Intro: Product Name:N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
CAS:1256490-31-9
Purity:98% Package:1KG;1USD
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Products Intro: Product Name:N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
CAS:1256490-31-9
Purity:99%;97%;98% Package:1g,2g,5g,100g,500g Remarks:customizable
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Products Intro: Product Name:Remdesivir Impurity 25
CAS:1256490-31-9
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Products Intro: Product Name:L-Alanine,N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-,1-methylethylester
CAS:1256490-31-9
Purity:97% Package:mgs,gs,kgs

N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester manufacturers
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Basic information
Product Name:N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
Synonyms:N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester;L-Alanine, N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester;2. N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine;N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-methylethyl este;isopropyl((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)-L-alaninate;(S)-Isopropyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate;N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-methyl...;EOS-61207
CAS:1256490-31-9
MF:C18H21N2O7P
MW:408.34
EINECS:1312995-182-4
Product Categories:
Mol File:1256490-31-9.mol
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Structure
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Chemical Properties
Melting point 62-66℃
Boiling point 514.3±60.0 °C(Predicted)
density 1.302
storage temp. 2-8°C
solubility Dichloromethane, Ethyl Acetate, Methanol
pka-5.78±0.70(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Usage And Synthesis
UsesN-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Preparation Products And Raw materials
Preparation ProductsSofosbuvir
Tag:N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester(1256490-31-9) Related Product Information
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol Remdesivir impurity-1 2-ethylbutyl ((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate Remdesivir R-18 Remdesivir Impurity 44 R-20 impurity 5 (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol R-19-impurity 4 Remdesivir impurity Remdesivir Impurity 39 (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
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