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| | XANTHOHUMOL Basic information |
| Product Name: | XANTHOHUMOL | | Synonyms: | 2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-;1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)- 2-propen-1-one;Xanthohumol1;1[2,4Dihydroxy6methoxy3(3methyl2buten1yl)phenyl]3(4hydroxyphenyl)2propen1one,1 [2,4 Dihydroxy 6 methoxy 3 (3 methyl 2 buten 1 yl)phenyl] 3 (4 hydroxyphenyl) 2 propen 1 one;(E/Z)-Xanthohumol;1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one, 10 mM in DMSO | | CAS: | 569-83-5 | | MF: | C21H22O5 | | MW: | 354.4 | | EINECS: | | | Product Categories: | Chalcones | | Mol File: | 569-83-5.mol |  |
| | XANTHOHUMOL Chemical Properties |
| Boiling point | 576.5±50.0 °C(Predicted) | | density | 1.244±0.06 g/cm3(Predicted) | | solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol | | form | powder | | pka | 7.47±0.45(Predicted) | | color | Yellow |
| | XANTHOHUMOL Usage And Synthesis |
| Uses | (E/Z)-Xanthohumol is a flavonoid isolated from hopfen[1]. | | Definition | ChEBI: Xanthohumol is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells. It has a role as a metabolite, an apoptosis inducer, an antineoplastic agent, an antiviral agent, an EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor and an anti-HIV-1 agent. It is a member of chalcones, a polyphenol and an aromatic ether. It is a conjugate acid of a xanthohumol(1-). | | References | [1] Rudolf H?nsel, et al. Desmethylxanthohumol: Isolierung aus Hopfen und Cyclisierung zu Flavanonen. Arch. Der Pharm.1988, 321, 1. |
| | XANTHOHUMOL Preparation Products And Raw materials |
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