Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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Tel: |
021-65675885 18964387627 |
Email: |
customer_service@efebio.com |
Products Intro: |
Product Name:LY382884 CAS:211566-75-5 Purity:98% Package:1mg;5mg;10mg
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:LY382884 CAS:211566-75-5 Purity:98.71% Package:1mg/RMB 5360;5mg/RMB 11200;10mg/RMB 14700
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3-Isoquinolinecarboxylic acid, 6-[(4-carboxyphenyl)methyl]decahydro-, (3S,4aR,6S,8aR)- manufacturers
- LY382884
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- $748.00 / 1mg
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2025-05-15
- CAS:211566-75-5
- Min. Order:
- Purity: 98.71%
- Supply Ability: 10g
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| 3-Isoquinolinecarboxylic acid, 6-[(4-carboxyphenyl)methyl]decahydro-, (3S,4aR,6S,8aR)- Basic information |
Product Name: | 3-Isoquinolinecarboxylic acid, 6-[(4-carboxyphenyl)methyl]decahydro-, (3S,4aR,6S,8aR)- | Synonyms: | 3-Isoquinolinecarboxylic acid, 6-[(4-carboxyphenyl)methyl]decahydro-, (3S,4aR,6S,8aR)-;LY 382884;LY382884;LY-382884 | CAS: | 211566-75-5 | MF: | C18H23NO4 | MW: | 317.38 | EINECS: | | Product Categories: | | Mol File: | 211566-75-5.mol | ![3-Isoquinolinecarboxylic acid, 6-[(4-carboxyphenyl)methyl]decahydro-, (3S,4aR,6S,8aR)- Structure](CAS/20210305/GIF/211566-75-5.gif) |
| 3-Isoquinolinecarboxylic acid, 6-[(4-carboxyphenyl)methyl]decahydro-, (3S,4aR,6S,8aR)- Chemical Properties |
Boiling point | 540.6±35.0 °C(Predicted) | density | 1.232±0.06 g/cm3(Predicted) | pka | 2.46±0.40(Predicted) |
| 3-Isoquinolinecarboxylic acid, 6-[(4-carboxyphenyl)methyl]decahydro-, (3S,4aR,6S,8aR)- Usage And Synthesis |
Description | LY382884 is a GLU(K5) receptor antagonist. LY382884 selectively binds the GLU(K5) kainate receptor subunit (K(b)=0.6 microM) and has 30 microM or greater affinity for cloned human AMPA receptor subtypes. GluR5-mediated glutamate signaling regulates hypothalamo-pituitary-adrenocortical stress responses at the paraventricular nucleus and median eminence. | Uses | LY382884 is a selective antagonist for GluR5 kainate receptor. LY382884 prevents the induction of NMDA receptor independent long-term potentiation (LTP)[1]. | Definition | ChEBI: LY382884 is a member of benzoic acids. | References | [1] Bortolotto ZA, et al., Kainate receptors are involved in synaptic plasticity. Nature. 1999 Nov 18;402(6759):297-301. DOI:10.1038/46290 |
| 3-Isoquinolinecarboxylic acid, 6-[(4-carboxyphenyl)methyl]decahydro-, (3S,4aR,6S,8aR)- Preparation Products And Raw materials |
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