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Shanghai Fuhe Chemistry Technology Co., Ltd.
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| Products Intro: |
Product Name:Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)-
CAS:220099-91-2
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Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)- manufacturers
- AZD 0328
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- $1980.00 / 50mg
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2025-07-19
- CAS:220099-91-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)- Basic information |
| Product Name: | Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)- | | Synonyms: | Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)-;AZD 0328;(R)-6',7'-dihydro-3'H-4-azaspiro[bicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine;(2R)-3H-1'-Azaspiro[furo[2,3-b]pyridine-2,3'-bicyclo[2.2.2]octane;(2R)-Spiro[1-azabicyclo[2.2.2]octane-3,2(3H)-furo[2,3-b]pyridine];UNII-2B218X5QIY | | CAS: | 220099-91-2 | | MF: | C13H16N2O | | MW: | 216.28 | | EINECS: | | | Product Categories: | | | Mol File: | 220099-91-2.mol | ![Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)- Structure](CAS/20180808/GIF/220099-91-2.gif) |
| | Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)- Chemical Properties |
| Boiling point | 361.1±42.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | pka | 9.59±0.20(Predicted) |
| | Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)- Usage And Synthesis |
| Uses | AZD0328 is a selective α7 nAChR partial agonist. AZD0328 selectively enhances midbrain dopaminergic neuronal activity and enhances cortical dopamine levels in rats. AZD0328 improves cognitive performance[1][2]. | | References | [1] Sydserff S, et al. Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes. DOI:10.1016/j.bcp.2009.07.005
[2] Castner SA, et al. Immediate and sustained improvements in working memory after selective stimulation of α7 nicotinic acetylcholine receptors. Biol Psychiatry. 2011 Jan 1;69(1):12-8. DOI:10.1016/j.biopsych.2010.08.006 |
| | Spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine], (2'R)- Preparation Products And Raw materials |
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